Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 3457

A sealed prediction that did not hold.

POU4F1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 3456, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 3457
    19 Oct 2026, 20:16 UTC

    POU4F1

    dopamine neurons, braak

    predictionPOU4F1 in dopamine neurons tracks Braak Lewy-body stage

    registered071fe3355fa00345

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    POU4F1 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    ca6b6ec58786e976e17a6d66…
    follows 5f965454f7c3…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 3457: POU4F1 in dopamine neurons, braak

cell type
POU4F1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for POU4F1 in dopamine neurons.

case closed: nothing better to follow up.