Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 0131

A sealed prediction that did not hold.

SMPD1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 130, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 0131
    16 Oct 2026, 17:18 UTC


    SMPD1

    dopamine neurons, resilience


    predictionSMPD1 in dopamine neurons differs in resilient donors (Lewy pathology, no parkinsonism)

    registered8864fabaa8d323bb

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign


    SMPD1 is not measured in dopamine neurons

    datasimulated substantia nigra cohort (84 donors)

    NOT TESTED

    707ad2268be3c73cc7544ef2…
    follows df56054d22da…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 0131: SMPD1 in dopamine neurons, resilience

cell type
SMPD1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "differs in resilient donors (Lewy pathology, no parkinsonism)" for SMPD1 in dopamine neurons.

case closed: nothing better to follow up.