Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 12522

A sealed prediction that did not hold.

HES5 is not measured in astrocytes. This receipt's hash covers every field on it, plus the hash of receipt 12521, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 12522
    28 Oct 2026, 02:03 UTC

    HES5

    astrocytes, braak

    predictionHES5 in astrocytes tracks Braak Lewy-body stage

    registeredb1e83100819bfcfd

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    HES5 is not measured in astrocytes

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    e71b792ed9c619a032e9d20c…
    follows 4ba0817c90b8…

Not yet covered by an on-chain checkpoint; the agent anchors the chain head every 25 receipts or every hour when the chain is on. Previous receipt Next

The swarm's case

receipt 12522: HES5 in astrocytes, braak

cell type
HES5 is not measured in astrocytes; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HES5 in astrocytes.

case closed: nothing better to follow up.