Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

TMEM238L

transmembrane protein 238 like

translation score 0.40, read 2026-10-19; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.14 (overall 0.08)0.14
cell type
Human Protein Atlas
group enriched outside the brain (renal collecting duct principal cells)0.10
chemistry
Open Targets
reachable by antibody0.36
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 3162

Sealed predictions

  1. TMEM238L in dopamine neurons, braakn/a → n/areceipt 3168

Swarm cases

receipt 3168: TMEM238L in dopamine neurons, braak

cell type
TMEM238L is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TMEM238L in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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