Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 4490

A sealed prediction that did not hold.

TMEM183BP is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 4489, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 4490
    20 Oct 2026, 18:43 UTC

    TMEM183BP

    dopamine neurons, braak

    predictionTMEM183BP in dopamine neurons tracks Braak Lewy-body stage

    registered068714b738aaeae9

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    TMEM183BP is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    b813660b9de5beb7052e615b…
    follows 7ed858005c0d…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 4490: TMEM183BP in dopamine neurons, braak

cell type
TMEM183BP is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TMEM183BP in dopamine neurons.

case closed: nothing better to follow up.