Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Receipt 1727

A sealed prediction that did not hold.

PRPS1L1 is not measured in dopamine neurons. This receipt's hash covers every field on it, plus the hash of receipt 1726, so changing any earlier receipt would break every one after it. Your browser recomputes it below.

The slip

  1. PARKINSON RECEIPTno. 1727
    18 Oct 2026, 05:07 UTC

    PRPS1L1

    dopamine neurons, braak

    predictionPRPS1L1 in dopamine neurons tracks Braak Lewy-body stage

    registered37137f048a415b42

    discoveryn/a

    replicationn/a

    neededp < 0.05 twice, same sign

    PRPS1L1 is not measured in dopamine neurons

    dataVolpato et al. 2025, ventral substantia nigra (18 donors)

    NOT TESTED

    89c4ec179ca7c3d303afddda…
    follows 9993d2e8b38b…

Covered by the on-chain checkpoint of receipt 10865 (2026-10-26 13:05 UTC). See the checkpoint on Robinhood Chain. Previous receipt Next

The swarm's case

receipt 1727: PRPS1L1 in dopamine neurons, braak

cell type
PRPS1L1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for PRPS1L1 in dopamine neurons.

case closed: nothing better to follow up.