Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

TAFA5

TAFA chemokine like family member 5

translation score 0.49, read 2026-10-22; 2 sealed predictions, 0 held; 3 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.03 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced in astrocytes (195 nCPM)1.00
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 220.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 6304

Sealed predictions

  1. TAFA5 in dopamine neurons, braakn/a → n/areceipt 6313
  2. TAFA5 in astrocytes, braakn/a → n/areceipt 6312

Swarm cases

receipt 6313: TAFA5 in dopamine neurons, braak

cell type
TAFA5 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TAFA5 in dopamine neurons.

case closed: nothing better to follow up.

receipt 6312: TAFA5 in astrocytes, braak

cell type
TAFA5 is not measured in astrocytes; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for TAFA5 in astrocytes.

case closed: nothing better to follow up.

Receipts

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