Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

SFN

stratifin

translation score 0.47, read 2026-10-23; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.02 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
7 Parkinson's trials, 0 stopped1.00
literature
PubMed
34 Parkinson's papers of 2,7460.53
pathways
Reactome
10 pathways; mostly mitochondrial quality control1.00

No case: the score is under the bar. Receipt 7736

Sealed predictions

  1. SFN in dopamine neurons, braakn/a → n/areceipt 7743

Swarm cases

receipt 7743: SFN in dopamine neurons, braak

cell type
SFN is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for SFN in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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