Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

SEPTIN5

septin 5

translation score 0.41, read 2026-10-22; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.03 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced, including brain excitatory neurons; strongest in choroid plexus epithelial cells0.75
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
6 Parkinson's papers of 360.74
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 6734

Sealed predictions

  1. SEPTIN5 in dopamine neurons, braakn/a → n/areceipt 6742

Swarm cases

receipt 6742: SEPTIN5 in dopamine neurons, braak

cell type
SEPTIN5 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for SEPTIN5 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts