Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

OPN1MW

opsin 1, medium wave sensitive

translation score 0.41, read 2026-10-25; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (cone photoreceptor cells)0.10
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 940.91
pathways
Reactome
4 pathways; mostly other0.30

No case: the score is under the bar. Receipt 9344

Sealed predictions

  1. OPN1MW in dopamine neurons, braakn/a → n/areceipt 9353

Swarm cases

receipt 9353: OPN1MW in dopamine neurons, braak

cell type
OPN1MW is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for OPN1MW in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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