Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

MICOS10

mitochondrial contact site and cristae organizing system subunit 10

translation score 0.49, read 2026-10-26; 2 sealed predictions, 0 held; 3 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced, including microglia; strongest in parietal cells0.75
chemistry
Open Targets
reachable by antibody0.36
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 10326

Sealed predictions

  1. MICOS10 in dopamine neurons, braakn/a → n/areceipt 10334
  2. MICOS10 in microglia, braakn/a → n/areceipt 10333

Swarm cases

receipt 10334: MICOS10 in dopamine neurons, braak

cell type
MICOS10 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MICOS10 in dopamine neurons.

case closed: nothing better to follow up.

receipt 10333: MICOS10 in microglia, braak

cell type
MICOS10 is not measured in microglia; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MICOS10 in microglia.

case closed: nothing better to follow up.

Receipts

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