Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

MATR3

matrin 3

translation score 0.30, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.06 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (megakaryocytes)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 1820.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 4256

Sealed predictions

  1. MATR3 in dopamine neurons, braakn/a → n/areceipt 4263

Swarm cases

receipt 4263: MATR3 in dopamine neurons, braak

cell type
MATR3 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for MATR3 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts