Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

IGHG3

immunoglobulin heavy constant gamma 3 (G3m marker)

translation score 0.30, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.07 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (plasma cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 930.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 4088

Sealed predictions

  1. IGHG3 in dopamine neurons, braakn/a → n/areceipt 4095

Swarm cases

receipt 4095: IGHG3 in dopamine neurons, braak

cell type
IGHG3 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for IGHG3 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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