Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

IFNG

interferon gamma

translation score 0.44, read 2026-10-18; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.11 from other evidence0.00
cell type
Human Protein Atlas
group enriched outside the brain (t-cells)0.10
chemistry
Open Targets
compounds already reach it: amg-811, fontolizumab, emapalumab0.90
trials
ClinicalTrials.gov
6 Parkinson's trials, 2 stopped0.73
literature
PubMed
14 Parkinson's papers of 3,3650.64
pathways
Reactome
7 pathways; mostly immune signalling0.90

No case: the score is under the bar. Receipt 2423

Sealed predictions

  1. IFNG in dopamine neurons, braakn/a → n/areceipt 2429

Swarm cases

receipt 2429: IFNG in dopamine neurons, braak

cell type
IFNG is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for IFNG in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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