Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

HTR1B

5-hydroxytryptamine receptor 1B

translation score 0.53, read 2026-10-25; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced, including brain inhibitory neurons; strongest in adrenal medulla cells0.75
chemistry
Open Targets
compounds already reach it: frovatriptan succinate, almotriptan malate, elzasonan +211.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
4 Parkinson's papers of 3490.79
pathways
Reactome
2 pathways; mostly other0.30

No case: the score is under the bar. Receipt 9977

Sealed predictions

  1. HTR1B in dopamine neurons, braakn/a → n/areceipt 9984

Swarm cases

receipt 9984: HTR1B in dopamine neurons, braak

cell type
HTR1B is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HTR1B in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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