Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

HMX3

H6 family homeobox 3

translation score 0.30, read 2026-10-21; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.05 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (tuft cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 410.91
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 5300

Sealed predictions

  1. HMX3 in dopamine neurons, braakn/a → n/areceipt 5308

Swarm cases

receipt 5308: HMX3 in dopamine neurons, braak

cell type
HMX3 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HMX3 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts