Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

HAPSTR1

HUWE1 associated protein modifying stress responses

translation score 0.42, read 2026-10-18; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.21 (overall 0.13)0.21
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 2290

Sealed predictions

  1. HAPSTR1 in dopamine neurons, braakn/a → n/areceipt 2296

Swarm cases

receipt 2296: HAPSTR1 in dopamine neurons, braak

cell type
HAPSTR1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for HAPSTR1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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