Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

GPR27

G protein-coupled receptor 27

translation score 0.43, read 2026-10-23; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.02 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 380.91
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 7406

Sealed predictions

  1. GPR27 in dopamine neurons, braakn/a → n/areceipt 7414

Swarm cases

receipt 7414: GPR27 in dopamine neurons, braak

cell type
GPR27 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for GPR27 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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