Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

FOXS1

forkhead box S1

translation score 0.33, read 2026-10-22; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
genetic association 0.05 (overall 0.03)0.05
cell type
Human Protein Atlas
group enriched outside the brain (peritubular myoid cells)0.10
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 6609

Sealed predictions

  1. FOXS1 in dopamine neurons, braakn/a → n/areceipt 6617

Swarm cases

receipt 6617: FOXS1 in dopamine neurons, braak

cell type
FOXS1 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for FOXS1 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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