Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

FERD3L

Fer3 like bHLH transcription factor

translation score 0.41, read 2026-10-24; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.02 from other evidence0.00
cell type
Human Protein Atlas
enriched in the midbrain (13 nTPM), where the nigral dopamine neurons sit0.90
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
2 Parkinson's papers of 190.85
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 8368

Sealed predictions

  1. FERD3L in dopamine neurons, braakn/a → n/areceipt 8375

Swarm cases

receipt 8375: FERD3L in dopamine neurons, braak

cell type
FERD3L is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for FERD3L in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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