Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

COXFA4L2

cytochrome c oxidase hypoxia associated subunit FA4L2

translation score 0.42, read 2026-10-17; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.31 from other evidence0.00
cell type
Human Protein Atlas
not in the Protein Atlas0.00
chemistry
Open Targets
compounds already reach it: me-344, metformin hydrochloride, metformin1.00
trials
ClinicalTrials.gov
4 Parkinson's trials, 0 stopped1.00
literature
PubMed
no papers tie it to Parkinson's yet1.00
pathways
Reactome
in no curated pathway0.00

No case: the score is under the bar. Receipt 1177

Sealed predictions

  1. COXFA4L2 in dopamine neurons, braakn/a → n/areceipt 1183

Swarm cases

receipt 1183: COXFA4L2 in dopamine neurons, braak

cell type
COXFA4L2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for COXFA4L2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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