Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

COX6A2

cytochrome c oxidase subunit 6A2

translation score 0.47, read 2026-10-17; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.32 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (thymic myoid cells)0.10
chemistry
Open Targets
reachable by antibody0.36
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 550.91
pathways
Reactome
4 pathways; mostly mitochondrial quality control1.00

No case: the score is under the bar. Receipt 1111

Sealed predictions

  1. COX6A2 in dopamine neurons, braakn/a → n/areceipt 1118

Swarm cases

receipt 1118: COX6A2 in dopamine neurons, braak

cell type
COX6A2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for COX6A2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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