Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

CNTF

ciliary neurotrophic factor

translation score 0.39, read 2026-10-22; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.04 from other evidence0.00
cell type
Human Protein Atlas
cell type enhanced outside the brain (melanocytes)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
37 Parkinson's papers of 2,2770.52
pathways
Reactome
1 pathway; mostly immune signalling0.90

No case: the score is under the bar. Receipt 6055

Sealed predictions

  1. CNTF in dopamine neurons, braakn/a → n/areceipt 6062

Swarm cases

receipt 6062: CNTF in dopamine neurons, braak

cell type
CNTF is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CNTF in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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