Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

CCL21

C-C motif chemokine ligand 21

translation score 0.37, read 2026-10-19; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.08 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (lymphatic endothelial cells)0.10
chemistry
Open Targets
reachable by antibody0.45
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
3 Parkinson's papers of 1,7310.82
pathways
Reactome
2 pathways; mostly other0.30

No case: the score is under the bar. Receipt 3397

Sealed predictions

  1. CCL21 in dopamine neurons, braakn/a → n/areceipt 3406

Swarm cases

receipt 3406: CCL21 in dopamine neurons, braak

cell type
CCL21 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for CCL21 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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