Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

BMAL2

basic helix-loop-helix ARNT like 2

translation score 0.38, read 2026-10-24; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.01 from other evidence0.00
cell type
Human Protein Atlas
expressed broadly, no clear home in brain cells0.40
chemistry
Open Targets
hard to drug0.00
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
1 Parkinson's papers of 550.91
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 8716

Sealed predictions

  1. BMAL2 in dopamine neurons, braakn/a → n/areceipt 8723

Swarm cases

receipt 8723: BMAL2 in dopamine neurons, braak

cell type
BMAL2 is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for BMAL2 in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts