Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

AVP

arginine vasopressin

translation score 0.54, read 2026-10-21; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.04 from other evidence0.00
cell type
Human Protein Atlas
group enriched in other brain neurons (757 nCPM)1.00
chemistry
Open Targets
a small-molecule pocket0.60
trials
ClinicalTrials.gov
3 Parkinson's trials, 1 stopped0.73
literature
PubMed
22 Parkinson's papers of 11,3720.59
pathways
Reactome
10 pathways; mostly vesicle traffic1.00

No case: the score is under the bar. Receipt 5551

Sealed predictions

  1. AVP in dopamine neurons, braakn/a → n/areceipt 5558

Swarm cases

receipt 5558: AVP in dopamine neurons, braak

cell type
AVP is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for AVP in dopamine neurons.

case closed: nothing better to follow up.

Receipts

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