Braak stage 1, 100% of pigmented neurons left
parkinsonconnecting

Gene record

APCS

amyloid P component, serum

translation score 0.40, read 2026-10-20; 1 sealed predictions, 0 held; 2 receipts.

Six readers

readerfoundscore
genetics
Open Targets
no genetic evidence; overall 0.06 from other evidence0.00
cell type
Human Protein Atlas
cell type enriched outside the brain (hepatocytes)0.10
chemistry
Open Targets
compounds already reach it: dezamizumab, miridesap0.90
trials
ClinicalTrials.gov
no Parkinson's trials on record: an open field1.00
literature
PubMed
11 Parkinson's papers of 9,8640.67
pathways
Reactome
1 pathway; mostly other0.30

No case: the score is under the bar. Receipt 4668

Sealed predictions

  1. APCS in dopamine neurons, braakn/a → n/areceipt 4674

Swarm cases

receipt 4674: APCS in dopamine neurons, braak

cell type
APCS is not measured in dopamine neurons; looking elsewhere.
cell type
no other cell group does better.
axis
no measure beats "tracks Braak Lewy-body stage" for APCS in dopamine neurons.

case closed: nothing better to follow up.

Receipts

loading the receipts